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Personality changes and paradoxical excitement are potential side effects. Clomethiazole can also be effective for controlling status epilepticus, but is used mainly to treat agitated states, especially alcoholic delirium tremens and associated seizures.
Major effector proteins for G-protein- coupled receptors include adenylate cyclase (ATP intracellular messenger cAMP), phospholipase C (phosphatidylinositol intracellular messengers inositol trisphosphate and diacylglycerol), as well as ion channel proteins.

 

When amphetamine-like substances are misused to enhance athletic performance (doping), there is a risk of dangerous physical overexertion. Because of the absence of a sense of fatigue, a drugged athlete may be able to mobilize ultimate energy reserves. In extreme situations, cardiovascular failure may result (B).
Vaccinations are designed to activate specific immune defenses. Interferons (IFN) are glycoproteins that, among other products, are released from virus-infected cells. In neighboring cells, interferon stimulates the production of “antiviral proteins. ” These inhibit the synthesis of viral proteins by (preferential) destruction of viral DNA or by suppressing its translation.

 

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