Drug Name Amitriptyline

The anthracycline antibiotics daunorubicin and adriamycin (doxorubicin) may induce cardiomyopathy. Bleomycin can also cause pulmonary fibrosis. The epipodophyllotoxins, etoposide and teniposide, interact with topoisomerase II, which functions to split, transpose, and reseal DNA strands; these agents cause strand breakage by inhibiting resealing. Inhibition of nucleobase synthesis (2).
For many drugs, teratogenic potency cannot be demonstrated; however, in the case of novel drugs it is usually not yet possible to define their teratogenic hazard. Drugs with established human teratogenicity include derivatives of vitamin A (etretinate, isotretinoin [used internally in skin diseases]), and oral anticoagulants.

 

Streptomycin and kanamycin are used predominantly in the treatment of tuberculosis. Note on spelling: -mycin designates origin from Streptomyces species; -micin (e. g. , gentamicin) from Micromonospora species. 2. Chloramphenicol inhibits peptide synthetase. It has bacteriostatic activity against a broad spectrum of pathogens.
This is so because the activity of elimination processes is concentration- dependent. The higher the drug concentration rises, the greater is the amount eliminated per unit of time. After several doses, the concentration will have climbed to a level at which the amounts eliminated and taken in per unit of time become equal, i. e. , a steady state is reached.