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The synthetic cannabinoids dronabinol and nabilone have antinauseant/ antiemetic effects that may benefit AIDS and cancer patients. For the past one decade, there has been an enhanced demand for more patient-friendly and compliant dosage forms. As a result, the demand for developing new technologies has been increasing annually1.
Bisphosphonates structurally mimic endogenous pyrophosphate, which inhibits precipitation and dissolution of bone minerals. They retard bone resorption by osteoclasts and, in part, also decrease bone mineralization. Indications include: tumor osteolysis, hypercalcemia, and Paget’s disease.

 

Aborad propulsion of intestinal contents is impeded when the latter are mixed with gas bubbles. Defoaming agents, such as dimethicone (dimethylpolysiloxane) and simethicone, in combination with charcoal, are given orally to promote separation of gaseous and semisolid contents. The smallest structural unit of skeletal musculature is the striated muscle fiber.
Synthesis of prostaglandins (PG), prostacyclin, and thromboxane proceeds via intermediary cyclic endoperoxides. In the case of PG, a cyclopentane ring forms in the acyl chain.

 

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