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Systemically administered epinephrine is important in the treatment of anaphylactic shock for combating hypotension. Bronchodilation. ?2-Adrenoceptor- mediated bronchodilation (e. g. , with terbutaline, fenoterol, or salbutamol) plays an essential part in the treatment of bronchial asthma (p. 328). Tocolysis.
With oral administration, dividing the total daily dose into several individual ones, e. g. , four, three, or two, offers a practical compromise. When the daily dose is given in several divided doses, the mean plasma level shows little fluctuation. In practice, it is found that a regimen of frequent regular drug ingestion is not well adhered to by patients. |
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